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Generalizing Gillespie’s direct method to enable network-free simulations

Gillespie’s direct method for stochastic simulation of chemical kinetics is a staple of computational systems biology research. However, the algorithm requires explicit enumeration of all reactions and all chemical species that may arise in the system. In many cases, this is not feasible due to the...

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Detalles Bibliográficos
Publicado en:Bull Math Biol
Main Authors: Suderman, Ryan, Mitra, Eshan D., Lin, Yen Ting, Erickson, Keesha E., Feng, Song, Hlavacek, William S.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162171/
https://ncbi.nlm.nih.gov/pubmed/29594824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11538-018-0418-2
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