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A systematic analysis of signaling reactivation and drug resistance
Increasing evidence suggests that the reactivation of initially inhibited signaling pathways causes drug resistance. Here, we analyze how network topologies affect signaling responses to drug treatment. Network-dependent drug resistance is commonly attributed to negative and positive feedback loops....
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8202068/ https://ncbi.nlm.nih.gov/pubmed/34038718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.109157 |
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