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A systematic analysis of signaling reactivation and drug resistance
Increasing evidence suggests that the reactivation of initially inhibited signaling pathways causes drug resistance. Here, we analyze how network topologies affect signaling responses to drug treatment. Network-dependent drug resistance is commonly attributed to negative and positive feedback loops....
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| 發表在: | Cell Rep |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8202068/ https://ncbi.nlm.nih.gov/pubmed/34038718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.109157 |
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