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A systematic analysis of signaling reactivation and drug resistance

Increasing evidence suggests that the reactivation of initially inhibited signaling pathways causes drug resistance. Here, we analyze how network topologies affect signaling responses to drug treatment. Network-dependent drug resistance is commonly attributed to negative and positive feedback loops....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Rep
Egile Nagusiak: Kholodenko, Boris N., Rauch, Nora, Kolch, Walter, Rukhlenko, Oleksii S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8202068/
https://ncbi.nlm.nih.gov/pubmed/34038718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.109157
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