SGK1-dependent stimulation of vascular smooth muscle cell osteo-/chondrogenic transdifferentiation by interleukin-18

The serum- and glucocorticoid-inducible kinase 1 (SGK1) is a key regulator of osteo-/chondrogenic transdifferentiation and subsequent calcification of vascular smooth muscle cells (VSMCs). The phenotypical transdifferentiation of VSMCs is associated with increased interleukin-18 (IL-18) levels and g...

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Detalhes bibliográficos
Publicado no:Pflugers Arch
Main Authors: Schelski, Nadeshda, Luong, Trang T. D., Lang, Florian, Pieske, Burkert, Voelkl, Jakob, Alesutan, Ioana
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2019
Assuntos:
Molecular and Cellular Mechanisms of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6533237/
https://ncbi.nlm.nih.gov/pubmed/30706178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-019-02256-5
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