Acid sphingomyelinase promotes SGK1-dependent vascular calcification

In chronic kidney disease (CKD), hyperphosphatemia is a key factor promoting medial vascular calcification, a common complication associated with cardiovascular events and high mortality. Vascular calcification involves osteo-/chondrogenic transdifferentiation of vascular smooth muscle cells (VSMCs)...

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Detalhes bibliográficos
Publicado no:Clin Sci (Lond)
Main Authors: Luong, Trang Thi Doan, Tuffaha, Rashad, Schuchardt, Mirjam, Moser, Barbara, Schelski, Nadeshda, Boehme, Beate, Gollmann-Tepeköylü, Can, Schramm, Clara, Holfeld, Johannes, Pieske, Burkert, Gulbins, Erich, Tölle, Markus, van der Giet, Markus, Lang, Florian, Eckardt, Kai-Uwe, Voelkl, Jakob, Alesutan, Ioana
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2021
Assuntos:
Cardiovascular System & Vascular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7859357/
https://ncbi.nlm.nih.gov/pubmed/33479769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20201122
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