SGK1 induces vascular smooth muscle cell calcification through NF-κB signaling

Medial vascular calcification, associated with enhanced mortality in chronic kidney disease (CKD), is fostered by osteo-/chondrogenic transdifferentiation of vascular smooth muscle cells (VSMCs). Here, we describe that serum- and glucocorticoid-inducible kinase 1 (SGK1) was upregulated in VSMCs unde...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Clin Invest
मुख्य लेखकों: Voelkl, Jakob, Luong, Trang T.D., Tuffaha, Rashad, Musculus, Katharina, Auer, Tilman, Lian, Xiaoming, Daniel, Christoph, Zickler, Daniel, Boehme, Beate, Sacherer, Michael, Metzler, Bernhard, Kuhl, Dietmar, Gollasch, Maik, Amann, Kerstin, Müller, Dominik N., Pieske, Burkert, Lang, Florian, Alesutan, Ioana
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Clinical Investigation 2018
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6025998/
https://ncbi.nlm.nih.gov/pubmed/29889103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI96477
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