SGK1 induces vascular smooth muscle cell calcification through NF-κB signaling

Medial vascular calcification, associated with enhanced mortality in chronic kidney disease (CKD), is fostered by osteo-/chondrogenic transdifferentiation of vascular smooth muscle cells (VSMCs). Here, we describe that serum- and glucocorticoid-inducible kinase 1 (SGK1) was upregulated in VSMCs unde...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Voelkl, Jakob, Luong, Trang T.D., Tuffaha, Rashad, Musculus, Katharina, Auer, Tilman, Lian, Xiaoming, Daniel, Christoph, Zickler, Daniel, Boehme, Beate, Sacherer, Michael, Metzler, Bernhard, Kuhl, Dietmar, Gollasch, Maik, Amann, Kerstin, Müller, Dominik N., Pieske, Burkert, Lang, Florian, Alesutan, Ioana
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6025998/
https://ncbi.nlm.nih.gov/pubmed/29889103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI96477
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