Zinc Inhibits Phosphate-Induced Vascular Calcification through TNFAIP3-Mediated Suppression of NF-κB

Background The high cardiovascular morbidity and mortality of patients with CKD may result in large part from medial vascular calcification, a process promoted by hyperphosphatemia and involving osteo-/chondrogenic transdifferentiation of vascular smooth muscle cells (VSMCs). Reduced serum zinc leve...

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Vydáno v:J Am Soc Nephrol
Hlavní autoři: Voelkl, Jakob, Tuffaha, Rashad, Luong, Trang T.D., Zickler, Daniel, Masyout, Jaber, Feger, Martina, Verheyen, Nicolas, Blaschke, Florian, Kuro-o, Makoto, Tomaschitz, Andreas, Pilz, Stefan, Pasch, Andreas, Eckardt, Kai-Uwe, Scherberich, Juergen E., Lang, Florian, Pieske, Burkert, Alesutan, Ioana
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2018
Témata:
Basic Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054342/
https://ncbi.nlm.nih.gov/pubmed/29654213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2017050492
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