Role of SGK1 in the Osteogenic Transdifferentiation and Calcification of Vascular Smooth Muscle Cells Promoted by Hyperglycemic Conditions

In diabetes mellitus, hyperglycemia promotes the osteogenic transdifferentiation of vascular smooth muscle cells (VSMCs) to enhance medial vascular calcification, a common complication strongly associated with cardiovascular disease and mortality. The mechanisms involved are, however, still poorly u...

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Publicado en:Int J Mol Sci
Main Authors: Poetsch, Florian, Henze, Laura A., Estepa, Misael, Moser, Barbara, Pieske, Burkert, Lang, Florian, Eckardt, Kai-Uwe, Alesutan, Ioana, Voelkl, Jakob
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583813/
https://ncbi.nlm.nih.gov/pubmed/33003561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21197207
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