Role of SGK1 in the Osteogenic Transdifferentiation and Calcification of Vascular Smooth Muscle Cells Promoted by Hyperglycemic Conditions

In diabetes mellitus, hyperglycemia promotes the osteogenic transdifferentiation of vascular smooth muscle cells (VSMCs) to enhance medial vascular calcification, a common complication strongly associated with cardiovascular disease and mortality. The mechanisms involved are, however, still poorly u...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Poetsch, Florian, Henze, Laura A., Estepa, Misael, Moser, Barbara, Pieske, Burkert, Lang, Florian, Eckardt, Kai-Uwe, Alesutan, Ioana, Voelkl, Jakob
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583813/
https://ncbi.nlm.nih.gov/pubmed/33003561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21197207
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