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Role of SGK1 in the Osteogenic Transdifferentiation and Calcification of Vascular Smooth Muscle Cells Promoted by Hyperglycemic Conditions

In diabetes mellitus, hyperglycemia promotes the osteogenic transdifferentiation of vascular smooth muscle cells (VSMCs) to enhance medial vascular calcification, a common complication strongly associated with cardiovascular disease and mortality. The mechanisms involved are, however, still poorly u...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Poetsch, Florian, Henze, Laura A., Estepa, Misael, Moser, Barbara, Pieske, Burkert, Lang, Florian, Eckardt, Kai-Uwe, Alesutan, Ioana, Voelkl, Jakob
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583813/
https://ncbi.nlm.nih.gov/pubmed/33003561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21197207
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