טוען...
Cbl interacts with multiple E2s in vitro and in cells
Many receptor tyrosine kinases (RTKs, such as EGFR, MET) are negatively regulated by ubiquitination and degradation mediated by Cbl proteins, a family of RING finger (RF) ubiquitin ligases (E3s). Loss of Cbl protein function is associated with malignant transformation driven by increased RTK activit...
שמור ב:
| הוצא לאור ב: | PLoS One |
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| Main Authors: | , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Public Library of Science
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6533038/ https://ncbi.nlm.nih.gov/pubmed/31120930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0216967 |
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