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Cbl and human myeloid neoplasms: the Cbl oncogene comes of age
Cbl was originally discovered in 1989 as the cellular homologue of the v-Cbl oncogene, the transforming gene of the Cas NS-1 murine retrovirus which causes myeloid leukemia and lymphomas in mice. Cbl is a member of a family of RING finger ubiquitin ligases which negatively regulate signaling by tyro...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2888780/ https://ncbi.nlm.nih.gov/pubmed/20501843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0610 |
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