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Cbl and human myeloid neoplasms: the Cbl oncogene comes of age

Cbl was originally discovered in 1989 as the cellular homologue of the v-Cbl oncogene, the transforming gene of the Cas NS-1 murine retrovirus which causes myeloid leukemia and lymphomas in mice. Cbl is a member of a family of RING finger ubiquitin ligases which negatively regulate signaling by tyro...

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Bibliographic Details
Main Authors: Kales, Stephen C., Ryan, Philip E., Nau, Marion M., Lipkowitz, Stanley
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888780/
https://ncbi.nlm.nih.gov/pubmed/20501843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0610
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