Loss of function Cbl-c mutations in solid tumors

Receptor Tyrosine Kinase (RTK) signaling is essential for normal biological processes and disruption of this regulation can lead to tumor initiation and progression. Cbl proteins (Cbl, Cbl-b and Cbl-c) are a family of RING finger (RF) ubiquitin ligases that negatively regulate a variety of RTKs, inc...

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Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Daniels, Silvano Rakeem, Liyasova, Mariya, Kales, Stephen C., Nau, Marion M., Ryan, Philip E., Green, Jeffrey E., Lipkowitz, Stanley
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2019
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602201/
https://ncbi.nlm.nih.gov/pubmed/31260484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0219143
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