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Cbl interacts with multiple E2s in vitro and in cells

Many receptor tyrosine kinases (RTKs, such as EGFR, MET) are negatively regulated by ubiquitination and degradation mediated by Cbl proteins, a family of RING finger (RF) ubiquitin ligases (E3s). Loss of Cbl protein function is associated with malignant transformation driven by increased RTK activit...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS One
मुख्य लेखकों: Liyasova, Mariya S., Ma, Ke, Voeller, Donna, Ryan, Philip E., Chen, Jinqiu, Klevit, Rachel E., Lipkowitz, Stanley
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6533038/
https://ncbi.nlm.nih.gov/pubmed/31120930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0216967
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