CD45Rb-low effector T cells require IL-4 to induce IL-10 in FoxP3 Tregs and to protect mice from inflammation

CD4(+) effector/memory T cells (Tem) represent a leading edge of the adaptive immune system responsible for protecting the body from infection, cancer, and other damaging processes. However, a subset of Tem cells with low expression of CD45Rb (Rb(Lo)Tem) has been shown to suppress inflammation despi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jones, Mark B., Alvarez, Carlos A., Johnson, Jenny L., Zhou, Julie Y., Morris, Nathan, Cobb, Brian A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6533033/
https://ncbi.nlm.nih.gov/pubmed/31120919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0216893
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