Live Attenuated Leishmania donovani Centrin Gene–Deleted Parasites Induce IL-23–Dependent IL-17–Protective Immune Response against Visceral Leishmaniasis in a Murine Model

No vaccine exists against visceral leishmaniasis. To develop effective vaccines, we have previously reported protective role of live attenuated centrin gene–deleted Leishmania donovani (LdCen(−/−)) parasites through induction of Th1 type immune response in mice, hamsters, and dogs. In this study, we...

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Pubblicato in:J Immunol
Autori principali: Banerjee, Antara, Bhattacharya, Parna, Dagur, Pradeep K., Karmakar, Subir, Ismail, Nevien, Joshi, Amritanshu B., Akue, Adovi D., KuKuruga, Mark, McCoy, John Philip, Dey, Ranadhir, Nakhasi, Hira L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532400/
https://ncbi.nlm.nih.gov/pubmed/29187586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700674
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