Regulation of cisplatin-resistant head and neck squamous cell carcinoma by the SRC/ETS-1 signaling pathway

BACKGROUND: We investigated the role of the ETS-1 transcription factor in Head and Neck Squamous Cell Carcinoma (HNSCC) in multiple cisplatin-resistant HNSCC cell lines. METHODS: We examined its molecular link with SRC and MEK/ERK pathways and determined the efficacy of either MEK/ERK inhibitor PD03...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Yang, Zejia, Liao, Jipei, Carter-Cooper, Brandon A., Lapidus, Rena G., Cullen, Kevin J., Dan, Hancai
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532223/
https://ncbi.nlm.nih.gov/pubmed/31118072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5664-7
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