Co-targeting EGFR and IKKβ/NF-κB signalling pathways in head and neck squamous cell carcinoma: a potential novel therapy for head and neck squamous cell cancer

BACKGROUND: Epidermal growth factor receptor (EGFR) plays an important role in head and neck squamous cell carcinoma (HNSCC) proliferation and therapy resistance, but the efficacy of targeting of EGFR for therapy has been limited. Here, we explore the molecular link between EGFR and inhibitor of κB...

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Vydáno v:Br J Cancer
Hlavní autoři: Li, Zhipeng, Liao, Jipei, Yang, Zejia, Choi, Eun Yong, Lapidus, Rena G., Liu, Xuefeng, Cullen, Kevin J., Dan, Hancai
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6353914/
https://ncbi.nlm.nih.gov/pubmed/30585254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0351-z
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