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Modeling HIV-1 Latency Using Primary CD4(+) T Cells from Virally Suppressed HIV-1-Infected Individuals on Antiretroviral Therapy
The low frequency of latently HIV-infected cells in vivo limits the testing of potential HIV cure strategies using cells from successfully suppressed individuals. To date, primary cell models of latency use cells infected in vitro. Primary CD4(+) T cell models carrying an individual’s endogenous HIV...
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| 發表在: | J Virol |
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| Main Authors: | , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6532074/ https://ncbi.nlm.nih.gov/pubmed/30918072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02248-18 |
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