Modeling HIV-1 Latency Using Primary CD4(+) T Cells from Virally Suppressed HIV-1-Infected Individuals on Antiretroviral Therapy

The low frequency of latently HIV-infected cells in vivo limits the testing of potential HIV cure strategies using cells from successfully suppressed individuals. To date, primary cell models of latency use cells infected in vitro. Primary CD4(+) T cell models carrying an individual’s endogenous HIV...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Takata, Hiroshi, Kessing, Cari, Sy, Aaron, Lima, Noemia, Sciumbata, Julia, Mori, Luisa, Jones, R. Brad, Chomont, Nicolas, Michael, Nelson L., Valente, Susana, Trautmann, Lydie
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2019
Sujets:
Virus-Cell Interactions
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532074/
https://ncbi.nlm.nih.gov/pubmed/30918072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02248-18
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