Modeling HIV-1 Latency Using Primary CD4(+) T Cells from Virally Suppressed HIV-1-Infected Individuals on Antiretroviral Therapy

The low frequency of latently HIV-infected cells in vivo limits the testing of potential HIV cure strategies using cells from successfully suppressed individuals. To date, primary cell models of latency use cells infected in vitro. Primary CD4(+) T cell models carrying an individual’s endogenous HIV...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Takata, Hiroshi, Kessing, Cari, Sy, Aaron, Lima, Noemia, Sciumbata, Julia, Mori, Luisa, Jones, R. Brad, Chomont, Nicolas, Michael, Nelson L., Valente, Susana, Trautmann, Lydie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532074/
https://ncbi.nlm.nih.gov/pubmed/30918072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02248-18
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