Histidine‐rich glycoprotein augments natural killer cell function by modulating PD‐1 expression via CLEC‐1B

Augmentation of natural killer (NK) cell cytotoxicity is one of the greatest challenges for cancer immunotherapy. Although histidine‐rich glycoprotein (HRG), a 75‐kDa glycoprotein with various immunomodulatory activities, reportedly elicits antitumor immunity, its effect on NK cell cytotoxicity is u...

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Foilsithe in:Pharmacol Res Perspect
Main Authors: Nishimura, Yoshito, Wake, Hidenori, Teshigawara, Kiyoshi, Wang, Dengli, Sakaguchi, Masakiyo, Otsuka, Fumio, Nishibori, Masahiro
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2019
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Original Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6531599/
https://ncbi.nlm.nih.gov/pubmed/31143450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.481
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