Histidine‐rich glycoprotein augments natural killer cell function by modulating PD‐1 expression via CLEC‐1B

Augmentation of natural killer (NK) cell cytotoxicity is one of the greatest challenges for cancer immunotherapy. Although histidine‐rich glycoprotein (HRG), a 75‐kDa glycoprotein with various immunomodulatory activities, reportedly elicits antitumor immunity, its effect on NK cell cytotoxicity is u...

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Detalhes bibliográficos
Publicado no:Pharmacol Res Perspect
Main Authors: Nishimura, Yoshito, Wake, Hidenori, Teshigawara, Kiyoshi, Wang, Dengli, Sakaguchi, Masakiyo, Otsuka, Fumio, Nishibori, Masahiro
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6531599/
https://ncbi.nlm.nih.gov/pubmed/31143450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.481
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