Histidine-Rich Glycoprotein Prevents Septic Lethality through Regulation of Immunothrombosis and Inflammation

Sepsis is a major cause of death worldwide. We show that a plasma protein histidine-rich glycoprotein (HRG) was decreased significantly in septic mice with cecal ligation and puncture (CLP) and supplementary treatment of septic mice with exogenous HRG improved survival, with strong inhibition of tig...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:EBioMedicine
Hoofdauteurs: Wake, Hidenori, Mori, Shuji, Liu, Keyue, Morioka, Yuta, Teshigawara, Kiyoshi, Sakaguchi, Masakiyo, Kuroda, Kosuke, Gao, Yuan, Takahashi, Hideo, Ohtsuka, Aiji, Yoshino, Tadashi, Morimatsu, Hiroshi, Nishibori, Masahiro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2016
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972547/
https://ncbi.nlm.nih.gov/pubmed/27333033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.06.003
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items