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Histidine-Rich Glycoprotein Prevents Septic Lethality through Regulation of Immunothrombosis and Inflammation

Sepsis is a major cause of death worldwide. We show that a plasma protein histidine-rich glycoprotein (HRG) was decreased significantly in septic mice with cecal ligation and puncture (CLP) and supplementary treatment of septic mice with exogenous HRG improved survival, with strong inhibition of tig...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:EBioMedicine
Egile Nagusiak: Wake, Hidenori, Mori, Shuji, Liu, Keyue, Morioka, Yuta, Teshigawara, Kiyoshi, Sakaguchi, Masakiyo, Kuroda, Kosuke, Gao, Yuan, Takahashi, Hideo, Ohtsuka, Aiji, Yoshino, Tadashi, Morimatsu, Hiroshi, Nishibori, Masahiro
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972547/
https://ncbi.nlm.nih.gov/pubmed/27333033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.06.003
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