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Dynamics of the EAG1 K(+) channel selectivity filter assessed by molecular dynamics simulations

EAG1 channels belong to the KCNH family of voltage gated potassium channels. They are expressed in several brain regions and increased expression is linked to certain cancer types. Recent cryo-EM structure determination finally revealed the structure of these channels in atomic detail, allowing comp...

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Détails bibliographiques
Publié dans:Biochem Biophys Res Commun
Auteurs principaux: Bernsteiner, Harald, Bründl, Michael, Stary-Weinzinger, Anna
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6531291/
https://ncbi.nlm.nih.gov/pubmed/28109880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2017.01.064
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