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Dynamics of the EAG1 K(+) channel selectivity filter assessed by molecular dynamics simulations

EAG1 channels belong to the KCNH family of voltage gated potassium channels. They are expressed in several brain regions and increased expression is linked to certain cancer types. Recent cryo-EM structure determination finally revealed the structure of these channels in atomic detail, allowing comp...

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Publicado en:Biochem Biophys Res Commun
Autores principales: Bernsteiner, Harald, Bründl, Michael, Stary-Weinzinger, Anna
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6531291/
https://ncbi.nlm.nih.gov/pubmed/28109880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2017.01.064
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