A carregar...

Cancer-associated mutation and beyond: The emerging biology of isocitrate dehydrogenases in human disease

Isocitrate dehydrogenases (IDHs) are critical metabolic enzymes that catalyze the oxidative decarboxylation of isocitrate to α-ketoglutarate (αKG), NAD(P)H, and CO(2). IDHs epigenetically control gene expression through effects on αKG-dependent dioxygenases, maintain redox balance and promote anaple...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Tommasini-Ghelfi, Serena, Murnan, Kevin, Kouri, Fotini M., Mahajan, Akanksha S., May, Jasmine L., Stegh, Alexander H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6530995/
https://ncbi.nlm.nih.gov/pubmed/31131326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaw4543
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!