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Endothelial Adora2a Activation Promotes Blood–Brain Barrier Breakdown and Cognitive Impairment in Mice with Diet-Induced Insulin Resistance

Obesity and insulin resistance elicit blood–brain barrier (BBB) breakdown in humans and animal models, but the relative contributions of the two pathologies remain poorly understood. These studies initially addressed the temporal progression of cerebrovascular dysfunction relative to dietary obesity...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Yamamoto, Masaki, Guo, De-Huang, Hernandez, Caterina M., Stranahan, Alexis M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529868/
https://ncbi.nlm.nih.gov/pubmed/30886019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2506-18.2019
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