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Blood–brain barrier breakdown promotes macrophage infiltration and cognitive impairment in leptin receptor-deficient mice
Accumulating evidence indicates that obesity accelerates the onset of cognitive decline. While mechanisms are still being identified, obesity promotes peripheral inflammation and increases blood–brain barrier (BBB) permeability. However, no studies have manipulated vascular permeability in obesity t...
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| Publicado no: | J Cereb Blood Flow Metab |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5363667/ https://ncbi.nlm.nih.gov/pubmed/27034250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X16642233 |
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