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Glucocorticoid-mediated activation of GSK3β promotes tau phosphorylation and impairs memory in type 2 diabetes

Type 2 diabetes is increasingly recognized as a risk factor for Alzheimer’s disease (AD), but the underlying mechanisms remain poorly understood. Hyperphosphorylation of the microtubule-associated protein tau has been reported in rodent models of diabetes, including db/db mice, which exhibit insulin...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Neurobiol Aging
मुख्य लेखकों: Dey, Aditi, Hao, Shuai, Wosiski-Kuhn, Marlena, Stranahan, Alexis M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5534373/
https://ncbi.nlm.nih.gov/pubmed/28609678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2017.05.010
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