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Glucocorticoid receptor activation impairs hippocampal plasticity by suppressing BDNF expression in obese mice

Diabetes and obesity are associated with perturbation of adrenal steroid hormones and impairment of hippocampal plasticity, but the question of whether these conditions recruit glucocorticoid-mediated molecular cascades that are comparable to other stressors has yet to be fully addressed. We have us...

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Publicat a:Psychoneuroendocrinology
Autors principals: Wosiski-Kuhn, Marlena, Erion, Joanna R., Gomez-Sanchez, Elise P., Gomez-Sanchez, Celso E., Stranahan, Alexis M.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426342/
https://ncbi.nlm.nih.gov/pubmed/24636513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psyneuen.2014.01.020
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