Endothelial Adora2a Activation Promotes Blood–Brain Barrier Breakdown and Cognitive Impairment in Mice with Diet-Induced Insulin Resistance

Obesity and insulin resistance elicit blood–brain barrier (BBB) breakdown in humans and animal models, but the relative contributions of the two pathologies remain poorly understood. These studies initially addressed the temporal progression of cerebrovascular dysfunction relative to dietary obesity...

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Vydáno v:J Neurosci
Hlavní autoři: Yamamoto, Masaki, Guo, De-Huang, Hernandez, Caterina M., Stranahan, Alexis M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2019
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529868/
https://ncbi.nlm.nih.gov/pubmed/30886019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2506-18.2019
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