Endothelial Adora2a Activation Promotes Blood–Brain Barrier Breakdown and Cognitive Impairment in Mice with Diet-Induced Insulin Resistance

Obesity and insulin resistance elicit blood–brain barrier (BBB) breakdown in humans and animal models, but the relative contributions of the two pathologies remain poorly understood. These studies initially addressed the temporal progression of cerebrovascular dysfunction relative to dietary obesity...

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Bibliografiset tiedot
Julkaisussa:J Neurosci
Päätekijät: Yamamoto, Masaki, Guo, De-Huang, Hernandez, Caterina M., Stranahan, Alexis M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 2019
Aiheet:
Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529868/
https://ncbi.nlm.nih.gov/pubmed/30886019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2506-18.2019
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