The Bile Acid TUDCA Improves Beta-Cell Mass and Reduces Insulin Degradation in Mice With Early-Stage of Type-1 Diabetes

Type 1 diabetes (T1D) is characterized by impairment in beta-cell mass and insulin levels, resulting in hyperglycemia and diabetic complications. Since diagnosis, appropriate control of glycaemia in T1D requires insulin administration, which can result in side effects, such as hypoglycemia. In this...

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Vydáno v:Front Physiol
Hlavní autoři: Bronczek, Gabriela Alves, Vettorazzi, Jean Franciesco, Soares, Gabriela Moreira, Kurauti, Mirian Ayumi, Santos, Cristiane, Bonfim, Maressa Fernandes, Carneiro, Everardo Magalhães, Balbo, Sandra Lucinei, Boschero, Antonio Carlos, Costa Júnior, José Maria
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Physiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529580/
https://ncbi.nlm.nih.gov/pubmed/31156453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.00561
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