Whole-Body ARHGAP21-Deficiency Improves Energetic Homeostasis in Lean and Obese Mice

Inhibition of Rab-GAP TBC1 domain family member 1 (TBC1D1) reduces body weight and increases energy expenditure in mice. Here, we assessed the possible involvement of GTPase activating protein 21 (ARHGAP21), a Rho-GAP protein, in energy homeostasis. Wild-type and whole-body ARHGAP21-haplodeficient m...

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Bibliografische gegevens
Gepubliceerd in:Front Endocrinol (Lausanne)
Hoofdauteurs: Soares, Gabriela Moreira, Zangerolamo, Lucas, Costa-Júnior, Jose Maria, Vettorazzi, Jean Franciesco, Carneiro, Everardo Magalhães, Saad, Sara Teresinha, Boschero, Antonio Carlos, Barbosa-Sampaio, Helena Cristina
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2019
Onderwerpen:
Endocrinology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548804/
https://ncbi.nlm.nih.gov/pubmed/31191459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2019.00338
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