The Bile Acid TUDCA Improves Beta-Cell Mass and Reduces Insulin Degradation in Mice With Early-Stage of Type-1 Diabetes

Type 1 diabetes (T1D) is characterized by impairment in beta-cell mass and insulin levels, resulting in hyperglycemia and diabetic complications. Since diagnosis, appropriate control of glycaemia in T1D requires insulin administration, which can result in side effects, such as hypoglycemia. In this...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Bronczek, Gabriela Alves, Vettorazzi, Jean Franciesco, Soares, Gabriela Moreira, Kurauti, Mirian Ayumi, Santos, Cristiane, Bonfim, Maressa Fernandes, Carneiro, Everardo Magalhães, Balbo, Sandra Lucinei, Boschero, Antonio Carlos, Costa Júnior, José Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529580/
https://ncbi.nlm.nih.gov/pubmed/31156453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.00561
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