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Protein malnutrition potentiates the amplifying pathway of insulin secretion in adult obese mice

Pancreatic beta cell (β) dysfunction is an outcome of malnutrition. We assessed the role of the amplifying pathway (AMP PATH) in β cells in malnourished obese mice. C57Bl-6 mice were fed a control (C) or a low-protein diet (R). The groups were then fed a high-fat diet (CH and RH). AMP PATH contribut...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Leite, Nayara Carvalho, de Paula, Flávia, Borck, Patrícia Cristine, Vettorazzi, Jean Franciesco, Branco, Renato Chaves Souto, Lubaczeuski, Camila, Boschero, Antonio Carlos, Zoppi, Claudio Cesar, Carneiro, Everardo Magalhães
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025848/
https://ncbi.nlm.nih.gov/pubmed/27633083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33464
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