Protein malnutrition potentiates the amplifying pathway of insulin secretion in adult obese mice

Pancreatic beta cell (β) dysfunction is an outcome of malnutrition. We assessed the role of the amplifying pathway (AMP PATH) in β cells in malnourished obese mice. C57Bl-6 mice were fed a control (C) or a low-protein diet (R). The groups were then fed a high-fat diet (CH and RH). AMP PATH contribut...

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Publicat a:Sci Rep
Autors principals: Leite, Nayara Carvalho, de Paula, Flávia, Borck, Patrícia Cristine, Vettorazzi, Jean Franciesco, Branco, Renato Chaves Souto, Lubaczeuski, Camila, Boschero, Antonio Carlos, Zoppi, Claudio Cesar, Carneiro, Everardo Magalhães
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025848/
https://ncbi.nlm.nih.gov/pubmed/27633083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33464
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