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Measuring thymic clonal deletion at the population level

Clonal deletion of T cells specific for self-antigens in the thymus has been widely studied, primarily by approaches that focus on a single receptor (using TCR transgenes) or a single specificity (using pMHC tetramers). However, less is known about clonal deletion at the population level. Here, we r...

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Vydáno v:J Immunol
Hlavní autoři: Breed, Elise R., Watanabe, Masashi, Hogquist, Kristin A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529273/
https://ncbi.nlm.nih.gov/pubmed/31010850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900191
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