Blood-derived DNA Methylation Signatures of Crohn’s Disease and Severity of Intestinal Inflammation

BACKGROUND & AIMS: Crohn’s disease is a relapsing and remitting inflammatory disorder with a variable clinical course. Although most patients present with an inflammatory phenotype (B1), approximately 20% of patients rapidly progresses to complicated disease, which includes stricturing (B2) with...

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Publicado no:Gastroenterology
Main Authors: Somineni, Hari K, Venkateswaran, Suresh, Kilaru, Varun, Marigorta, Urko M, Mo, Angela, Okou, David T, Kellermayer, Richard, Mondal, Kajari, Cobb, Dawayland, Walters, Thomas D, Griffiths, Anne, Noe, Joshua D, Crandall, Wallace V, Rosh, Joel R, Mack, David R, Heyman, Melvin B, Baker, Susan S, Stephens, Michael C, Baldassano, Robert N, Markowitz, James F, Dubinsky, Marla C, Cho, Judy, Hyams, Jeffrey S, Denson, Lee A, Gibson, Greg, Cutler, David J, Conneely, Karen N, Smith, Alicia K, Kugathasan, Subra
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529254/
https://ncbi.nlm.nih.gov/pubmed/30779925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2019.01.270
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