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Neutrophil GM-CSF signaling in inflammatory bowel disease patients is influenced by non-coding genetic variants
Neutrophil dysfunction and GM-CSF auto-antibodies are observed in pediatric and adult patients with Crohn’s disease (CD). We associated damaging coding variants with low GM-CSF induced STAT5 stimulation index (GMSI) in pediatric CD patients and implicated variation of neutrophil GM-CSF signaling in...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6591305/ https://ncbi.nlm.nih.gov/pubmed/31235766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45701-2 |
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