Translation affects mRNA stability in a codon-dependent manner in human cells

mRNA translation decodes nucleotide into amino acid sequences. However, translation has also been shown to affect mRNA stability depending on codon composition in model organisms, although universality of this mechanism remains unclear. Here, using three independent approaches to measure exogenous a...

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Bibliografiska uppgifter
I publikationen:eLife
Huvudupphovsmän: Wu, Qiushuang, Medina, Santiago Gerardo, Kushawah, Gopal, DeVore, Michelle Lynn, Castellano, Luciana A, Hand, Jacqelyn M, Wright, Matthew, Bazzini, Ariel Alejandro
Materialtyp: Artigo
Språk:Inglês
Publicerad: eLife Sciences Publications, Ltd 2019
Ämnen:
Chromosomes and Gene Expression
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529216/
https://ncbi.nlm.nih.gov/pubmed/31012849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.45396
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