FMRP - G-quadruplex mRNA - miR-125a interactions: Implications for miR-125a mediated translation regulation of PSD-95 mRNA

Fragile X syndrome, the most common inherited form of intellectual disability, is caused by the CGG trinucleotide expansion in the 5’-untranslated region of the Fmr1 gene on the X chromosome, which silences the expression of the fragile X mental retardation protein (FMRP). FMRP has been shown to bin...

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Udgivet i:PLoS One
Main Authors: DeMarco, Brett, Stefanovic, Snezana, Williams, Allison, Moss, Kathryn R., Anderson, Bart R., Bassell, Gary J., Mihailescu, Mihaela Rita
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529005/
https://ncbi.nlm.nih.gov/pubmed/31112584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0217275
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