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dCK negatively regulates the NRF2/ARE axis and ROS production in pancreatic cancer
OBJECTIVES: Decreased deoxycytidine kinase (dCK) expression is a reported indicator of gemcitabine efficacy in pancreatic cancer, due to the impact of this kinase on gemcitabine metabolism. The transcription factor NF‐E2 p45‐related factor 2 (NRF2, also called Nfe2l2), a master regulator of redox ho...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Cell Prolif |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
John Wiley and Sons Inc.
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6528851/ https://ncbi.nlm.nih.gov/pubmed/29701272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12456 |
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