PRMT5 enhances tumorigenicity and glycolysis in pancreatic cancer via the FBW7/cMyc axis

BACKGROUND: The epigenetic factor protein arginine methyltransferase 5 (PRMT5) has been reported to play vital roles in a wide range of cellular processes, such as gene transcription, genomic organization, differentiation and cell cycle control. However, its role in pancreatic cancer remains unclear...

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Vydáno v:Cell Commun Signal
Hlavní autoři: Qin, Yi, Hu, Qiangsheng, Xu, Jin, Ji, Shunrong, Dai, Weixing, Liu, Wensheng, Xu, Wenyan, Sun, Qiqing, Zhang, Zheng, Ni, Quanxing, Zhang, Bo, Yu, Xianjun, Xu, Xiaowu
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440122/
https://ncbi.nlm.nih.gov/pubmed/30922330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-019-0344-4
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