TCF7L2 positively regulates aerobic glycolysis via the EGLN2/HIF-1α axis and indicates prognosis in pancreatic cancer

Patients with pancreatic ductal adenocarcinoma have much worse prognoses, and much effort has been directed toward understanding the molecular biological aspects of this disease. Accumulated evidence suggests that constitutive activation of the Wnt/β-catenin signalling contributes to the oncogenesis...

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Vydáno v:Cell Death Dis
Hlavní autoři: Xiang, Jinfeng, Hu, Qiangsheng, Qin, Yi, Ji, Shunrong, Xu, Wenyan, Liu, Wensheng, Shi, Si, Liang, Chen, Liu, Jiang, Meng, Qingcai, Liang, Dingkong, Ni, Quanxing, Xu, Jin, Zhang, Bo, Yu, Xianjun
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833500/
https://ncbi.nlm.nih.gov/pubmed/29476053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0367-6
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