TCF7L2 positively regulates aerobic glycolysis via the EGLN2/HIF-1α axis and indicates prognosis in pancreatic cancer

Patients with pancreatic ductal adenocarcinoma have much worse prognoses, and much effort has been directed toward understanding the molecular biological aspects of this disease. Accumulated evidence suggests that constitutive activation of the Wnt/β-catenin signalling contributes to the oncogenesis...

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Publicado en:Cell Death Dis
Main Authors: Xiang, Jinfeng, Hu, Qiangsheng, Qin, Yi, Ji, Shunrong, Xu, Wenyan, Liu, Wensheng, Shi, Si, Liang, Chen, Liu, Jiang, Meng, Qingcai, Liang, Dingkong, Ni, Quanxing, Xu, Jin, Zhang, Bo, Yu, Xianjun
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833500/
https://ncbi.nlm.nih.gov/pubmed/29476053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0367-6
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