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Beta-glucuronidase catalyzes deconjugation and activation of curcumin-glucuronide in bone

The biological basis for documented in vivo bone-protective effects of turmeric-derived curcumin is unclear since curcumin is barely detectable in serum, being rapidly conjugated to form what is thought to be an inactive glucuronide. Studies were therefore undertaken to test the postulate that anti-...

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Bibliografiske detaljer
Udgivet i:J Nat Prod
Main Authors: Kunihiro, Andrew G, Luis, Paula B, Brickey, Julia A, Frye, Jen B, Chow, H-H. Sherry, Schneider, Claus, Funk, Janet L
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528680/
https://ncbi.nlm.nih.gov/pubmed/30794412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jnatprod.8b00873
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