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Bone-specific metabolism of dietary polyphenols in resorptive bone diseases

SCOPE: Curcumin prevents bone loss in resorptive bone diseases and inhibits osteoclast formation, a key process driving bone loss. Curcumin circulates as an inactive glucuronide that can be deconjugated in situ by bone’s high β-glucuronidase (GUSB) content, forming the active aglycone. Because curcu...

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Detalhes bibliográficos
Publicado no:Mol Nutr Food Res
Main Authors: Kunihiro, Andrew G, Luis, Paula B, Frye, Jennifer B, Chew, Wade, Chow, H-H. Sherry, Schneider, Claus, Funk, Janet L
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7712627/
https://ncbi.nlm.nih.gov/pubmed/32506808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.202000072
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