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Beta-glucuronidase catalyzes deconjugation and activation of curcumin-glucuronide in bone

The biological basis for documented in vivo bone-protective effects of turmeric-derived curcumin is unclear since curcumin is barely detectable in serum, being rapidly conjugated to form what is thought to be an inactive glucuronide. Studies were therefore undertaken to test the postulate that anti-...

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Detalhes bibliográficos
Publicado no:J Nat Prod
Main Authors: Kunihiro, Andrew G, Luis, Paula B, Brickey, Julia A, Frye, Jen B, Chow, H-H. Sherry, Schneider, Claus, Funk, Janet L
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528680/
https://ncbi.nlm.nih.gov/pubmed/30794412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jnatprod.8b00873
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