Genomic Characterization of Prostatic Ductal Adenocarcinoma Identifies a High Prevalence of DNA Repair Gene Mutations

PURPOSE: Ductal prostate cancer (dPC) is a rare variant of prostatic adenocarcinoma associated with poor outcomes. Although its histopathologic features are well characterized, the underlying molecular hallmarks of this aggressive subtype are not well described. We sought to provide a comprehensive...

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Dettagli Bibliografici
Pubblicato in:JCO Precis Oncol
Autori principali: Schweizer, Michael T., Antonarakis, Emmanuel S., Bismar, Tarek A., Guedes, Liana B., Cheng, Heather H., Tretiakova, Maria S., Vakar-Lopez, Funda, Klemfuss, Nola, Konnick, Eric Q., Mostaghel, Elahe A., Hsieh, Andrew C., Nelson, Peter S., Yu, Evan Y., Montgomery, R. Bruce, True, Lawrence D., Epstein, Jonathan I., Lotan, Tamara L., Pritchard, Colin C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Clinical Oncology 2019
Soggetti:
Original Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528668/
https://ncbi.nlm.nih.gov/pubmed/31123724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.18.00327
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